A Rare Case of Solitary Kidney Metastasis Following Primary Laryngeal Squamous Cell Carcinoma

Main Article Content

Sharon Del Vecchio
Robert Ellis
Kylie Gallagher
Keng Lim Ng
Li Ma
Geoffrey Strutton
Simon Wood

Keywords

laryngeal squamous cell carcinoma, PET-MRI, renal cell carcinoma, smoking, solitary kidney metastasis

Abstract

Laryngeal cancer is the 14th most common malignancy worldwide, and its common subtype squamous cell carcinoma (SCC) is highly associated with tobacco use and long-term alcohol consumption. The incidence of distant metastasis from a primary laryngeal cancer has been reported to be very low, between 6.5% and 8.5%, according to published tumour registry data. Distant metastases of laryngeal SCC most commonly involve the lung, liver, bone and mediastinum, seldom involving the kidney. Renal metastasis has been well established in many other cancers such as lymphoma, lung, breast and gastric carcinoma. This report discusses the rare case of a solitary renal metastasis following a primary laryngeal SCC.

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References

1. Stewart BW, Wild CP (eds). World Cancer Report 2014. International Agency for Research on Cancer; 2014.
2. Yucel OT, Yilmaz T, Unal OF, Turan E. Distant metastases in laryngeal squamous cell carcinoma. J Exp Clin Cancer Res. 1999;18(3):285–8.
3. Liu WW, Zeng ZY, Guo ZM, Xu GP, Yang AK, Zhang Q. [Distant metastases and their significant indicators in laryngeal cancer]. Zhonghua Er Bi Yan Hou Ke Za Zhi. 2003;38(3):221–4.
4. Spector JG, Sessions DG, Haughey BH, Chao KS, Simpsn J, El Mofty S, et al. Delayed regional metastases, distant metastases, and second primary malignancies in squamous cell carcinomas of the larynx and hypopharynx. Laryngoscope. 2001;111(6):1079–87. https://doi.org/10.1097/00005537-200106000-00028
5. Bailey JE, Roubidoux MA, Dunnick NR. Secondary renal neoplasms. Abdom Imaging. 1998;23(3):266–74. https://doi.org/10.1007/s002619900337
6. Paul NS, Harden P, Fowler RC, Chalmers AG. Renal metastases from a squamous cell carcinoma of the larynx. Br J Radiol. 1999;72(863):1117–19. https://doi.org/10.1259/bjr.72.863.10700832
7. Lecoeuvre V, Degardin M, Penel N, Grosjean J, Bonodeau F. [Renal colic due to kidney metastase from larynx cancer]. Rev Med Interne. 2003;24(1):67–9. https://doi.org/10.1016/S0248-8663(02)00011-5
8. Erbag G, Dolaşık İ, Erdoğan S, Şener SY, Dursun İH. Renal metastasis: An uncommon site of laryngeal cancer metastasis. Abant Med J. 2013;2(3):252–3. https://doi.org/10.5505/abantmedj.2013.64936
9. Fidler IJ. The pathogenesis of cancer metastasis: The ‘seed and soil’ hypothesis revisited. Nat Rev Cancer. 2003;3(6):453–8. https://doi.org/10.1038/nrc1098